SCHEMBL538790

SCHEMBL538790

C[NH+](C)c1ccccc1.Cc1ccc([Al-](c2ccc(C)cc2)(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
ACHE P22303 2/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
HPGD P15428 2/20 0.35
TDP1 Q9NUW8 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
CA12 O43570 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA1 P00915 1/20 0.32
MCOLN3 Q8TDD5 1/20 0.31
POLB P06746 2/20 0.31
CYP2C19 P33261 2/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085715 0.87
SCHEMBL538803 0.82 ACHE (0.33) LMNAACHETSHRALOX12
Trimethylammonium SCHEMBL298235 0.79 ACHE (0.47) LMNAACHETSHRALOX12HPGD
SCHEMBL539317 0.79 ACHE (0.39) LMNAACHETSHRALOX12HPGD
SCHEMBL1450688 0.76 ACHE (0.57) LMNAACHETSHRALOX12TDP1
SCHEMBL135100 0.75 ACHE (0.40) LMNAACHETSHRALOX12HPGD
Lithium Ion SCHEMBL137877 0.74 ACHE (0.53) LMNAACHETSHRALOX12HPGD
SCHEMBL134650 0.74 ACHE (0.53) LMNAACHETSHRALOX12HPGD
Potassium Ion SCHEMBL134458 0.74 ACHE (0.53) LMNAACHETSHRALOX12HPGD
SCHEMBL538969 0.73 TDP1 (0.32) LMNAACHETSHRALOX12HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1706437-B1 DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH CHEVRON PHILLIPS CHEMICAL CO (US) 2016-01-20 EP claimed
EP-1711543-B1 CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS CHEVRON PHILLIPS CHEMICAL CO (US) 2011-08-24 EP claimed
EP-1773899-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO (US) 2009-02-11 EP claimed
JP-2007520597-A 2007-07-26 JP claimed
JP-2007518871-A 2007-07-12 JP claimed
EP-1778749-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2007-05-02 EP claimed
EP-1773899-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2007-04-18 EP claimed
US-7199073-B2 Resins that yield low haze films and the process for their production CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2007-04-03 US claimed
US-7148298-B2 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) 2006-12-12 US claimed
EP-1711543-A2 CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS Chevron Phillips Chemical Company LP (US) 2006-10-18 EP claimed
US-6982306-B2 Stannoxy-substituted metallocene catalysts for olefin and acetylene polymerization CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) 2006-01-03 US claimed
US-20050288461-A1 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2005-12-29 US claimed
US-20050288462-A1 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILIPS CHEMICAL COMPANY, L.P. 2005-12-29 US claimed
WO-2005070977-A1 DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-08-04 WO claimed
WO-2005068519-A2 CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-07-28 WO claimed
US-20050159300-A1 Dual metallocene catalyst for producing film resins with good machine direction (MD) elmendorf tear strength CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-07-21 US claimed
US-20050153830-A1 contact product of a first metallocene compound, a second metallocene compound, a chemically-treated solid oxide, and an organoaluminum compound; useful properties in impact, tear, adhesion, sealing, extruder motor loads and pressures at comparable melt index values, and neck-in and draw-down. CHEVRON PHILIPS CHEMICAL COMPANY LP 2005-07-14 US claimed
WO-2005052011-A1 CATALYST COMPOSITIONS FOR PRODUCING POLYOLEFINS IN THE ABSENCE OF COCATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-06-09 WO claimed
US-20050113245-A1 STANNOXY-SUBSTITUTED METALLOCENE CATALYSTS FOR OLEFIN AND ACETYLENE POLYMERIZATION CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-05-26 US claimed
US-20050113243-A1 Catalyst compositions for producing polyolefins in the absence of cocatalysts CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2005-05-26 US claimed