SCHEMBL538969

SCHEMBL538969

C[NH+](C)c1ccccc1.Cc1ccc([Al-](c2ccc(C)cc2C)(c2ccc(C)cc2C)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.32
ALDH1A1 P00352 3/20 0.32
TP53 P04637 1/20 0.32
CYP2A6 P11509 1/20 0.32
LMNA P02545 2/20 0.32
NPC1 O15118 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 2/20 0.31
ALOX12 P18054 2/20 0.31
NFE2L2 Q16236 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
GFER P55789 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KMT2A Q03164 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylaniline SCHEMBL3898633 0.83 RAB9A (0.33) TDP1TP53CYP2A6LMNANPC1
SCHEMBL1450871 0.80 TDP1 (0.46) TDP1ALDH1A1TP53CYP2A6NPC1
Lithium Ion SCHEMBL136411 0.78 TDP1 (0.44) TDP1ALDH1A1TP53CYP2A6NPC1
SCHEMBL132865 0.78 TDP1 (0.44) TDP1ALDH1A1TP53CYP2A6NPC1
Potassium Ion SCHEMBL134597 0.78 TDP1 (0.44) TDP1ALDH1A1TP53CYP2A6NPC1
SCHEMBL538837 0.76 TDP1 (0.38) TDP1ALDH1A1TP53CYP2A6LMNA
SCHEMBL134687 0.75 ALDH1A1 (0.33) TDP1ALDH1A1TP53CYP2A6LMNA
SCHEMBL29614764 0.75 ALDH1A1 (0.33) TDP1ALDH1A1TP53CYP2A6LMNA
SCHEMBL538774 0.74 TDP1 (0.34) TDP1ALDH1A1TP53CYP2A6LMNA
SCHEMBL538790 0.73 LMNA (0.40) TDP1ALDH1A1LMNANPC1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1706437-B1 DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH CHEVRON PHILLIPS CHEMICAL CO (US) 2016-01-20 EP claimed
EP-1711543-B1 CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS CHEVRON PHILLIPS CHEMICAL CO (US) 2011-08-24 EP claimed
EP-1773899-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO (US) 2009-02-11 EP claimed
JP-2007518871-A 2007-07-12 JP claimed
EP-1778749-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2007-05-02 EP claimed
US-7199073-B2 Resins that yield low haze films and the process for their production CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2007-04-03 US claimed
US-7148298-B2 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) 2006-12-12 US claimed
US-7119153-B2 Dual metallocene catalyst for producing film resins with good machine direction (MD) elmendorf tear strength CHEVRON PHILLIPS CHEMICAL COMPANY LP 2006-10-10 US claimed
EP-1706437-A1 DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH Chevron Phillips Chemical Company LP (US) 2006-10-04 EP claimed
EP-1692194-A1 CATALYST COMPOSITIONS FOR PRODUCING POLYOLEFINS IN THE ABSENCE OF COCATALYSTS Chevron Phillips Chemical Company LP (US) 2006-08-23 EP claimed
WO-2006004709-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2006-01-12 WO claimed
US-6982306-B2 Stannoxy-substituted metallocene catalysts for olefin and acetylene polymerization CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) 2006-01-03 US claimed
US-20050288461-A1 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2005-12-29 US claimed
US-20050288462-A1 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILIPS CHEMICAL COMPANY, L.P. 2005-12-29 US claimed
WO-2005070977-A1 DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-08-04 WO claimed
US-20050159300-A1 Dual metallocene catalyst for producing film resins with good machine direction (MD) elmendorf tear strength CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-07-21 US claimed
US-20050153830-A1 contact product of a first metallocene compound, a second metallocene compound, a chemically-treated solid oxide, and an organoaluminum compound; useful properties in impact, tear, adhesion, sealing, extruder motor loads and pressures at comparable melt index values, and neck-in and draw-down. CHEVRON PHILIPS CHEMICAL COMPANY LP 2005-07-14 US claimed
WO-2005052011-A1 CATALYST COMPOSITIONS FOR PRODUCING POLYOLEFINS IN THE ABSENCE OF COCATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-06-09 WO claimed
US-20050113243-A1 Catalyst compositions for producing polyolefins in the absence of cocatalysts CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2005-05-26 US claimed
US-20050113245-A1 STANNOXY-SUBSTITUTED METALLOCENE CATALYSTS FOR OLEFIN AND ACETYLENE POLYMERIZATION CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-05-26 US claimed