Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316478 | 0.77 | IDO1 (0.47) | IDO1ALOX15HSD17B10TP53SMN1; SMN2 | |
| SCHEMBL29104485 | 0.77 | IDO1 (0.46) | IDO1ALOX15HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL4045966 | 0.77 | IDO1 (0.46) | IDO1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL4045894 | 0.73 | HSD11B1 (0.41) | TSHRCYP1A2CYP2C19 | |
| SCHEMBL63014 | 0.71 | RAB9A (0.41) | IDO1ALOX15HSD17B10TP53SMN1; SMN2 | |
| SCHEMBL11669563 | 0.70 | BRD4 (0.40) | KMT2ALMNABRD4 | |
| SCHEMBL6003439 | 0.70 | IDO1 (0.49) | IDO1MAPK1 | |
| SCHEMBL6002844 | 0.70 | CDK2 (0.38) | IDO1MAPK1 | |
| SCHEMBL4049259 | 0.69 | DRD1 (0.41) | ALOX15HSD17B10HPGDMAPTKMT2A | |
| SCHEMBL4592137 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202279-B1 | Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders | GEORGETOWN UNIVERSITY (US) | 2007-04-10 | — | — | US | claimed |