Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.81 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426764 | 1.00 | KCNH2 (0.81) | KCNH2LARS1DRD2GRIN1GRIN2B | |
| SCHEMBL14426763 | 1.00 | KCNH2 (0.81) | KCNH2LARS1DRD2GRIN1GRIN2B | |
| SCHEMBL14426759 | 1.00 | KCNH2 (0.81) | KCNH2LARS1DRD2GRIN1GRIN2B | |
| SCHEMBL5390476 | 1.00 | KCNH2 (0.81) | KCNH2LARS1DRD2GRIN1GRIN2B | |
| SCHEMBL5395590 | 1.00 | KCNH2 (0.81) | KCNH2LARS1DRD2GRIN1GRIN2B | |
| SCHEMBL14426761 | 0.89 | KCNH2 (0.65) | KCNH2LARS1DRD2GRIN1GRIN2B | |
| SCHEMBL5396751 | 0.89 | KCNH2 (0.65) | KCNH2LARS1DRD2GRIN1GRIN2B | |
| SCHEMBL14426770 | 0.88 | KCNH2 (0.64) | KCNH2LARS1DRD2HRH3 | |
| SCHEMBL5390274 | 0.88 | KCNH2 (0.64) | KCNH2LARS1DRD2HRH3 | |
| SCHEMBL14426758 | 0.87 | KCNH2 (0.63) | KCNH2LARS1DRD2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259174-B2 | Imidazolidinone compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2007-08-21 | — | — | US | disclosed |
| US-20050267164-A1 | Imidazolidinone compounds | NATIONAL HEALTH RESEARCH INSTITUTES | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267164-A1 | Imidazolidinone compounds | MLX, EPX, ZYX | KCNH2 1792/4885LARS1 4223/4885DRD2 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.