Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.87 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385056 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5388335 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5385053 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL6981090 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL10098821 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL1697179 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5391762 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5391765 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5395653 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL418425 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253182-B2 | Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments | SOFOTEC GMBH & CO. KG (DE) | 2007-08-07 | — | — | US | disclosed |
| US-6613795-B2 | Respiratory system disorders; muscle relaxants | Noe, Christian (DE) | 2003-09-02 | — | — | US | disclosed |
| US-20020173536-A1 | Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments | CHRISTIAN NOE AND ERNST MUTSCHLER | 2002-11-21 | — | — | US | disclosed |
| US-6307060-B1 | ANTISPASMODIC AGENTS | Noe, Christian | 2001-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173536-A1 | Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments | CYP2A13, CYP3A43, HCAR2 | ALDH1A1 505/4885CYP1A2 17/4885CYP3A4 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.