Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.87 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385056 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5388335 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5385053 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5388340 | 1.00 | ALDH1A1 (0.98) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL10098821 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL1697179 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5391762 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5391765 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL5395653 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL418425 | 0.99 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253182-B2 | Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments | SOFOTEC GMBH & CO. KG (DE) | 2007-08-07 | — | — | US | disclosed |
| EP-1369414-A1 | Enantiomerically pure Arylcycloalkyl hydroxycarboxylic esters, processes for their preparation and their use as modulators of muscarinic receptors | Noe, Christian R. (AT) | 2003-12-10 | — | — | EP | disclosed |
| EP-0937041-B1 | Use of a pharmaceutically acceptable salt of (3R,2'R)-3-[(Cyclopently-hydroxyphenylacetyl)oxy]-1,1-dimethyl-pyrrolidinium for the preparation of a medicament | NOE CHRISTIAN R (DE) | 2003-04-23 | — | — | EP | disclosed |
| EP-0937041-A1 | PURE ENANTIOMER BASIC ARYL-CYCLOALKYL-HYDROXYCARBOXYLIC ACID ESTERS, PROCESS FOR PREPARING THE SAME AND THEIR USE IN MEDICAMENTS | Noe, Christian R. (DE) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998021183-A1 | PURE ENANTIOMER BASIC ARYL-CYCLOALKYL-HYDROXYCARBOXYLIC ACID ESTERS, PROCESS FOR PREPARING THE SAME AND THEIR USE IN MEDICAMENTS | NOE CHRISTIAN R (AT) | 1998-05-22 | — | — | WO | disclosed |