Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3883769 | 1.00 | ALDH1A1 (0.30) | — | |
| SCHEMBL16859 | 0.89 | — | — | |
| SCHEMBL5483305 | 0.89 | ALDH1A1 (0.33) | — | |
| SCHEMBL6995610 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL11329859 | 0.80 | — | — | |
| Methane SCHEMBL16428422 | 0.80 | — | — | |
| SCHEMBL538884 | 0.80 | — | — | |
| Bromide SCHEMBL3220866 | 0.68 | — | — | |
| Carbon Tetrachloride SCHEMBL9012663 | 0.68 | TSHR (0.57) | — | |
| SCHEMBL159721 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410154-B2 | Tetrazole compounds for reducing uric acid | WELLSTAT THERAPEUTICS CORPORATION (US) | 2013-04-02 | — | — | US | disclosed |
| EP-2415744-A1 | FLUORENE COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20110206653-A1 | TETRAZOLE COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110160433-A1 | BENZYLIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2011-06-30 | — | — | US | disclosed |