Terephthalamide

Terephthalamide

SCHEMBL538997

C=C.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.63
TSHR P16473 2/20 0.63
POLB P06746 1/20 0.63
CYP3A4 P08684 1/20 0.63
MAPT P10636 1/20 0.63
CYP2C19 P33261 1/20 0.63
RECQL P46063 1/20 0.63
BLM P54132 1/20 0.63
PMP22 Q01453 1/20 0.63
HSD17B10 Q99714 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
PARP10 Q53GL7 10/20 0.62
PARP4 Q9UKK3 2/20 0.62
PARP15 Q460N3 2/20 0.62
ALDH1A1 P00352 1/20 0.62
KMT2A Q03164 1/20 0.62
PARP14 Q460N5 1/20 0.62
PARP16 Q8N5Y8 1/20 0.62
PARP11 Q9NR21 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL15168441 1.00 PARP1 (0.63) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL23774 0.93 PARP1 (0.71) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL15328883 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL1906838 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL28360111 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL689841 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL11512422 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL1087289 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL7508927 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL29102653 0.90 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414446-A1 FLAME RESISTANT SEMIAROMATIC POLYAMIDE RESIN COMPOSITION AND ARTICLES THEREFROM E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
WO-2010117708-A1 FLAME RESISTANT SEMIAROMATIC POLYAMIDE RESIN COMPOSITION AND ARTICLES THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
JP-54155251-A None JP disclosed
WO-2023084378-A1 METHOD OF CONVERTING POLY(ETHYLENE TEREPHTHALATE) TO TEREPHTHALIC ACID SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-19 WO disclosed
CN-113956654-A High-temperature-resistant nylon master batch and preparation method thereof 安徽众诚塑胶科技有限公司 2022-01-21 CN disclosed
WO-2021108533-A1 POLYAMIDE-METAL LAMINATES DUPONT POLYMERS, INC. (US) 2021-06-03 WO disclosed
EP-2860213-A1 Multilayer films including thermoplastic silicone block copolymers 3M Innovative Properties Company of 3M Center (US) 2015-04-15 EP disclosed
EP-1963897-B1 MULTILAYER FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2015-01-21 EP disclosed
US-8524370-B2 Multilayer films including thermoplastic silicone block copolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-03 US disclosed
EP-1963899-B1 FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2013-08-28 EP disclosed
EP-2627699-A1 STAIN-RESISTANT ARTICLES Solvay Specialty Polymers USA, LLC. (US) 2013-08-21 EP disclosed
US-20100221511-A1 MULTILAYER FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2010-09-02 US disclosed
EP-1963899-A2 FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M Innovative Properties Company (US) 2008-09-03 EP disclosed
EP-1963897-A2 MULTILAYER FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M Innovative Properties Company (US) 2008-09-03 EP disclosed
EP-1852457-A1 PROCESS FOR PRODUCING THERMOPLASTIC-POLYMER SOLUTION Asahi Kasei Chemicals Corporation (JP) 2007-11-07 EP disclosed
US-20070177272-A1 MULTILAYER FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2007-08-02 US disclosed
US-20070177273-A1 FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2007-08-02 US disclosed
WO-2007075900-A2 MULTILAYER FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO disclosed
WO-2007073502-A2 FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-06-28 WO disclosed
JP-S54155251-A POLYAMIDE RESIN COMPOSITION MITSUBISHI CHEM IND LTD 1979-12-07 JP disclosed