SCHEMBL538998

SCHEMBL538998

NC(=O)c1ccc(C(=O)N2CC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
HPGD P15428 4/20 0.61
PKM P14618 1/20 0.53
POLB P06746 1/20 0.53
CA12 O43570 7/20 0.53
CA1 P00915 7/20 0.53
CA2 P00918 7/20 0.53
CA7 P43166 7/20 0.53
CA9 Q16790 7/20 0.53
CA14 Q9ULX7 7/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
MAPK1 P28482 1/20 0.50
PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL4983893 0.92 HPGD (0.53) ALDH1A1HPGDPKMPOLBCA12
SCHEMBL472215 0.91 HPGD (0.76) ALDH1A1HPGDCA12CA1CA2
SCHEMBL10412133 0.91 HPGD (0.69) ALDH1A1HPGDPOLBCA12CA1
Terephthalamide SCHEMBL1160127 0.91 HPGD (0.76) ALDH1A1HPGDCA12CA1CA2
SCHEMBL5694406 0.91 HPGD (0.76) ALDH1A1HPGDCA12CA1CA2
SCHEMBL3004567 0.90 POLB (0.69) HPGDPOLBMEN1KMT2ALMNA
SCHEMBL4560822 0.90 HPGD (0.80) ALDH1A1HPGDCA12CA1CA2
SCHEMBL367513 0.90 HPGD (0.80) ALDH1A1HPGDCA12CA1CA2
SCHEMBL367607 0.90 HPGD (0.80) ALDH1A1HPGDCA12CA1CA2
SCHEMBL11857269 0.90 HPGD (0.80) ALDH1A1HPGDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024095104-A1 METHOD OF CONVERTING POLY(ETHYLENE TEREPHTHALATE) TO TEREPHTHALIC ACID SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-05-10 WO claimed
WO-2023084378-A1 METHOD OF CONVERTING POLY(ETHYLENE TEREPHTHALATE) TO TEREPHTHALIC ACID SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-19 WO claimed
EP-4180413-A1 METHOD OF CONVERTING POLY(ETHYLENE TEREPHTHALATE) TO TEREPHTHALIC ACID SHPP Global Technologies B.V. (NL) 2023-05-17 EP claimed
US-20220267211-A1 MIXED WASTE PLASTICS COMPATIBILIZERS FOR ASPHALT Alliance for Energy Innovation, LLC 2022-08-25 US claimed
EP-2414446-A1 FLAME RESISTANT SEMIAROMATIC POLYAMIDE RESIN COMPOSITION AND ARTICLES THEREFROM E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
WO-2010117708-A1 FLAME RESISTANT SEMIAROMATIC POLYAMIDE RESIN COMPOSITION AND ARTICLES THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
JP-54155251-A None JP disclosed
WO-2024095104-A1 METHOD OF CONVERTING POLY(ETHYLENE TEREPHTHALATE) TO TEREPHTHALIC ACID SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-05-10 WO disclosed
WO-2023084378-A1 METHOD OF CONVERTING POLY(ETHYLENE TEREPHTHALATE) TO TEREPHTHALIC ACID SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-19 WO disclosed
EP-4180413-A1 METHOD OF CONVERTING POLY(ETHYLENE TEREPHTHALATE) TO TEREPHTHALIC ACID SHPP Global Technologies B.V. (NL) 2023-05-17 EP disclosed
US-20220267211-A1 MIXED WASTE PLASTICS COMPATIBILIZERS FOR ASPHALT Alliance for Energy Innovation, LLC 2022-08-25 US disclosed
CN-114206997-A Resin composition and molded article 住友化学株式会社 2022-03-18 CN disclosed
CN-114207027-A Liquid crystal polyester resin pellet, process for producing the same, and process for producing molded article 住友化学株式会社 2022-03-18 CN disclosed
EP-1852457-A1 PROCESS FOR PRODUCING THERMOPLASTIC-POLYMER SOLUTION Asahi Kasei Chemicals Corporation (JP) 2007-11-07 EP disclosed
US-20070177273-A1 FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2007-08-02 US disclosed
US-20070177272-A1 MULTILAYER FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2007-08-02 US disclosed
WO-2007075900-A2 MULTILAYER FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO disclosed
WO-2007073502-A2 FILMS INCLUDING THERMOPLASTIC SILICONE BLOCK COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-06-28 WO disclosed
JP-S54155251-A POLYAMIDE RESIN COMPOSITION MITSUBISHI CHEM IND LTD 1979-12-07 JP disclosed
US-4062819-A Polyamide blends having improved processing characteristics EMERY INDUSTRIES, INC. (US) 1977-12-13 US disclosed