SCHEMBL472215

SCHEMBL472215

NC(=O)c1ccc(C(=O)N2CCCC2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.76
ALDH1A1 P00352 3/20 0.76
MAPK1 P28482 1/20 0.61
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
MLYCD O95822 2/20 0.59
MEN1 O00255 1/20 0.58
TSHR P16473 1/20 0.58
KMT2A Q03164 1/20 0.58
MAOA P21397 1/20 0.57
KDM4E B2RXH2 1/20 0.55
L3MBTL3 Q96JM7 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
USP2 O75604 1/20 0.55
MBTD1 Q05BQ5 1/20 0.55
TP53BP1 Q12888 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL1160127 1.00 HPGD (0.76) HPGDALDH1A1MAPK1CA12CA1
SCHEMBL5694406 1.00 HPGD (0.76) HPGDALDH1A1MAPK1CA12CA1
SCHEMBL1194042 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1
SCHEMBL367607 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1
Terephthalamide SCHEMBL13724808 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1
SCHEMBL4560822 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1
SCHEMBL367513 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1
SCHEMBL11857269 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1
Terephthalamide SCHEMBL1160108 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1
SCHEMBL1160398 0.98 HPGD (0.80) HPGDALDH1A1MAPK1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101987915-B Polymer composite containing polyalcohol and co-stabilizer DU PONT 2012-09-05 CN claimed
EP-1628972-B1 INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI AVENTIS DEUTSCHLAND (DE) 2009-04-22 EP claimed
US-7365088-B2 Indazole-derivatives as factor Xa inhibitors SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-04-29 US claimed
EP-1226202-B1 COPOLYAMIDE BASED ON TETRAMETHYLENE TEREPHTHALAMIDE AND HEXAMETHYLENE TEREPHTHALAMIDE DSM IP ASSETS BV (NL) 2006-06-07 EP claimed
EP-1628972-A1 INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS Sanofi-Aventis Deutschland GmbH (DE) 2006-03-01 EP claimed
US-20040235824-A1 Indazole-derivatives as factor Xa inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-11-25 US claimed
WO-2004101556-A1 INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-11-25 WO claimed
EP-1479675-A1 Indazole-derivatives as factor Xa inhibitors Aventis Pharma Deutschland GmbH (DE) 2004-11-24 EP claimed
US-6747120-B2 COPOLYMER HAS MELTING POINT HIGHER THAN 290 DEGREES CELCIUS, HIGH CRYSTALLINITY AND GOOD DIMENSIONAL STABILITY DSM IP ASSETS B.V. (NL) 2004-06-08 US claimed
JP-2003528165-A 2003-09-24 JP claimed
US-20020183479-A1 Copolyamide based on tetramethylene terephthalamide and hexamethylene tereohthalamide DSM IP ASSETS B.V. (NL) 2002-12-05 US claimed
EP-1226202-A1 COPOLYAMIDE BASED ON TETRAMETHYLENE TEREPHTHALAMIDE AND HEXAMETHYLENE TEREPHTHALAMIDE DSM N.V. (NL) 2002-07-31 EP claimed
WO-2001025311-A1 COPOLYAMIDE BASED ON TETRAMETHYLENE TEREPHTHALAMIDE AND HEXAMETHYLENE TEREPHTHALAMIDE DSM N.V. (NL) 2001-04-12 WO claimed
EP-0411709-B1 Polyamide composition DSM NV (NL) 1994-06-01 EP claimed
US-5084552-A Tetramethylenediamine with adipic acid, terephthalic acid and isophthalic acid terpolyamide for moldings and films STAMICARBON B.V. (NL) 1992-01-28 US claimed
EP-0411709-A1 Polyamide composition DSM N.V. (NL) 1991-02-06 EP claimed
CN-114672018-B Preparation method and application of modified polyamide 上海红叶塑料制品有限公司 2024-03-08 CN disclosed
CN-111225940-B Polymerization process 杜邦聚合物公司 2023-10-10 CN disclosed
US-5084552-A Tetramethylenediamine with adipic acid, terephthalic acid and isophthalic acid terpolyamide for moldings and films STAMICARBON B.V. (NL) 1992-01-28 US disclosed
EP-0411709-A1 Polyamide composition DSM N.V. (NL) 1991-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235824-A1 Indazole-derivatives as factor Xa inhibitors F11, F12, F5 HPGD 678/4885ALDH1A1 1259/4885MAPK1 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.