Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529212 | 0.92 | NPSR1 (0.48) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL527937 | 0.86 | ALDH1A1 (0.48) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL529354 | 0.85 | MAPT (0.55) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL528549 | 0.84 | MAPT (0.56) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL528306 | 0.82 | KDM4E (0.67) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL528797 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL528332 | 0.81 | ALDH1A1 (0.51) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL528225 | 0.81 | MAPT (0.46) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL528351 | 0.78 | MAPT (0.48) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL3281840 | 0.77 | KMT2A (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |