Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528697 | 0.92 | MAPT (0.42) | ALDH1A1MAPTHTTGAANPSR1 | |
| SCHEMBL528384 | 0.90 | OXTR (0.44) | ALDH1A1MAPTHTTNPC1POLB | |
| SCHEMBL528225 | 0.88 | MAPT (0.46) | ALDH1A1MAPTHTTGAANPC1 | |
| SCHEMBL528938 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTHTTGAANPSR1 | |
| SCHEMBL527903 | 0.83 | MAPT (0.52) | ALDH1A1MAPTNPC1POLBLMNA | |
| SCHEMBL528851 | 0.83 | RXFP1 (0.46) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL528549 | 0.81 | MAPT (0.56) | ALDH1A1MAPTHTTGAALMNA | |
| SCHEMBL539192 | 0.81 | MAPT (0.49) | ALDH1A1MAPTHTTGAANPSR1 | |
| SCHEMBL527889 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTGAANPSR1 | |
| SCHEMBL528053 | 0.80 | MAPT (0.55) | ALDH1A1MAPTHTTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |