Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394159 | 0.84 | PRKCQ (0.38) | PRKCQAXLPARP14ITKHTR6 | |
| SCHEMBL14035868 | 0.82 | BRD4 (0.43) | PRKCQAXLKCNH2PARP14ITK | |
| SCHEMBL5390131 | 0.81 | PRKCQ (0.43) | PRKCQAXLKCNH2ITKHTR6 | |
| Hydrochloric Acid SCHEMBL5382559 | 0.80 | PRKCQ (0.42) | PRKCQAXLKCNH2ITKHTR6 | |
| SCHEMBL5392817 | 0.79 | AXL (0.41) | PRKCQAXLITKHTR6PLK4 | |
| SCHEMBL21460289 | 0.76 | KCNH2 (0.46) | AXLKCNH2ITKPLK4BRD4 | |
| SCHEMBL5398964 | 0.76 | AXL (0.39) | PRKCQAXLITKHTR6PLK4 | |
| SCHEMBL5403382 | 0.75 | BRD4 (0.43) | AXLKCNH2PLK4BRD4ATAD2 | |
| SCHEMBL20612430 | 0.75 | PRKCQ (0.39) | PRKCQAXLPARP14ITKHTR6 | |
| SCHEMBL5388199 | 0.75 | PRKCQ (0.37) | PRKCQAXLPARP14ITKHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-7070629-B2 | Dye composition comprising at least one diaminopyrazole oxidation base, at least one paraphenylenediamine oxidation base comprising a cyclic amino group, and at least one coupler | L'OREAL, S.A. (FR) | 2006-07-04 | — | — | US | claimed |
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | L'OREAL S.A. (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1432389-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | claimed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | claimed |
| WO-2003028689-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2003-04-10 | — | — | WO | claimed |
| CN-1372459-A | Dyeing composition for keratinous fibres comprising a p-phenylenediamine derivative having a pyrrolidinyl group | OREAL (FR) | 2002-10-02 | — | — | CN | claimed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | claimed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | claimed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-7070629-B2 | Dye composition comprising at least one diaminopyrazole oxidation base, at least one paraphenylenediamine oxidation base comprising a cyclic amino group, and at least one coupler | L'OREAL, S.A. (FR) | 2006-07-04 | — | — | US | disclosed |
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | L'OREAL S.A. (FR) | 2004-11-25 | — | — | US | disclosed |
| CN-1532193-A | Dimethyl-[1-(4-nitrophenyl) pyrrolidine-3-yl] amine | �ź㴫 | 2004-09-29 | — | — | CN | disclosed |
| EP-1432389-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | disclosed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | disclosed |
| WO-2003028689-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2003-04-10 | — | — | WO | disclosed |
| CN-1372459-A | Dyeing composition for keratinous fibres comprising a p-phenylenediamine derivative having a pyrrolidinyl group | OREAL (FR) | 2002-10-02 | — | — | CN | disclosed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | KRT18, AOC1, DPYD | PRKCQ 494/4885AXL 2436/4885KCNH2 714/4885 |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | KRT18, CKAP4, KRTCAP2 | PRKCQ 122/4885AXL 3030/4885KCNH2 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.