Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.43 |
| ▸ | BPTF | Q12830 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390337 | 0.84 | PRKCZ (0.37) | BRD4ATAD2BPTFKCNH2PRKCZ | |
| SCHEMBL5386930 | 0.81 | BRD4 (0.48) | BRD4ATAD2BPTFKCNH2PRKCZ | |
| SCHEMBL5395259 | 0.79 | CHEK1 (0.41) | BRD4ATAD2BPTFPRKCZPRKD2 | |
| SCHEMBL5383201 | 0.76 | BRD4 (0.39) | BRD4ATAD2BPTFPRKCZPRKD2 | |
| SCHEMBL5392170 | 0.75 | PRKCQ (0.41) | BRD4ATAD2KCNH2HRH4HRH3 | |
| SCHEMBL10192577 | 0.73 | PRKCZ (0.49) | BRD4ATAD2KCNH2PRKCZPRKD2 | |
| SCHEMBL5392079 | 0.71 | PLK4 (0.56) | KCNH2PRKCZPRKD2HRH4HRH3 | |
| SCHEMBL14035868 | 0.70 | BRD4 (0.43) | BRD4ATAD2KCNH2HRH4HRH3 | |
| SCHEMBL4066935 | 0.70 | HTR6 (0.47) | BRD4ATAD2KCNH2PRKCZPRKD2 | |
| SCHEMBL18403938 | 0.69 | HRH3 (0.41) | BRD4ATAD2KCNH2PRKCZHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-7070629-B2 | Dye composition comprising at least one diaminopyrazole oxidation base, at least one paraphenylenediamine oxidation base comprising a cyclic amino group, and at least one coupler | L'OREAL, S.A. (FR) | 2006-07-04 | — | — | US | claimed |
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | L'OREAL S.A. (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1432389-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | claimed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | claimed |
| WO-2003028689-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2003-04-10 | — | — | WO | claimed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | claimed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | claimed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-7070629-B2 | Dye composition comprising at least one diaminopyrazole oxidation base, at least one paraphenylenediamine oxidation base comprising a cyclic amino group, and at least one coupler | L'OREAL, S.A. (FR) | 2006-07-04 | — | — | US | disclosed |
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | L'OREAL S.A. (FR) | 2004-11-25 | — | — | US | disclosed |
| EP-1432389-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | disclosed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | disclosed |
| WO-2003028689-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2003-04-10 | — | — | WO | disclosed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | KRT18, AOC1, DPYD | BRD4 667/4885ATAD2 3376/4885BPTF 2634/4885 |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | KRT18, CKAP4, KRTCAP2 | BRD4 1273/4885ATAD2 2804/4885BPTF 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.