Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL29389282 | 1.00 | TSHR (0.48) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28693414 | 1.00 | TSHR (0.48) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL599308 | 0.96 | TSHR (0.44) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL6132118 | 0.96 | TSHR (0.44) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL25227095 | 0.92 | TSHR (0.52) | TSHRTP53SRD5A2KMT2AALDH1A1 | |
| Benzoic Acid SCHEMBL1713123 | 0.92 | TSHR (0.52) | TSHRTP53SRD5A2KMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL247734 | 0.90 | CYP2C9 (0.44) | TSHRTP53SRD5A2CA1CA2 | |
| Isophthalic Acid SCHEMBL8734977 | 0.85 | CYP2C9 (0.46) | CA1CA2CA12CA6CA9 | |
| SCHEMBL177283 | 0.84 | MAPT (0.41) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL9250529 | 0.82 | TSHR (0.55) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1784 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011347-A | Regeneration preparation method of PETG or PCTG copolyester | 中国石油化工股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122010724-A | Method for depolymerizing copolyesters, depolymerized products and application of depolymerized products in preparing copolyesters | 中国石油化工股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4735256-A1 | MULTILAYER OPTICAL FILM | 3M Innovative Properties Company (US) | 2026-05-06 | — | — | EP | claimed |
| EP-3790930-B1 | NOISE REDUCING FILLED POLYESTER | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-08-27 | — | — | EP | claimed |
| US-12391826-B2 | Noise reducing filled polyester | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2025-08-19 | — | — | US | claimed |
| WO-2025003850-A1 | MULTILAYER OPTICAL FILM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-01-02 | — | — | WO | claimed |
| CN-115260505-B | Tough furan dicarboxylic acid polyester and preparation method thereof | 中国科学院成都有机化学有限公司 | 2024-11-22 | — | — | CN | claimed |
| US-20240294747-A1 | NOISE REDUCING FILLED POLYESTER | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2024-09-05 | — | — | US | claimed |
| US-12065565-B2 | Noise reducing filled polyester | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2024-08-20 | — | — | US | claimed |
| CN-118176249-A | Encapsulation of flame retardants by atomic layer deposition to improve flame retardant formulations | 高新特殊工程塑料全球技术有限公司 | 2024-06-11 | — | — | CN | claimed |
| WO-1998013266-A1 | TRANSPARENT OXYGEN-SCAVENGING ARTICLE INCLUDING BIAXIALLY-ORIENTED POLYESTER | CONTINENTAL PET TECHNOLOGIES, INC. (US) | 1998-04-02 | — | — | WO | claimed |
| US-5439961-A | Increasing the strength by blending with a biphenyl compound, molding and biaxial stretching | KAO CORPORATION (JP) | 1995-08-08 | — | — | US | claimed |
| EP-0636655-A2 | Halogen-free flame retardant compositions | GENERAL ELECTRIC COMPANY (US) | 1995-02-01 | — | — | EP | claimed |
| US-5306767-A | Good appearance; chemical resistance | GE PLASTICS JAPAN, LTD. (JP) | 1994-04-26 | — | — | US | claimed |
| EP-0502960-A1 | FILM LAMINATE | EASTMAN KODAK COMPANY (US) | 1992-09-16 | — | — | EP | claimed |
| US-5043398-A | Grafting of functional compounds onto functional oxymethylene polymer backbones, with diisocyanate coupling agents, and the graft polymers thereof | HOECHST CELANESE CORPORATION (US) | 1991-08-27 | — | — | US | claimed |
| WO-1991008107-A1 | FILM LAMINATE | EASTMAN KODAK COMPANY (US) | 1991-06-13 | — | — | WO | claimed |
| EP-0397493-A2 | Grafting of functional compounds onto functional oxymethylene polymer backbones, with diisocyanate coupling agents and the graft polymers thereof | HOECHST CELANESE CORPORATION (US) | 1990-11-14 | — | — | EP | claimed |
| EP-0273152-A2 | Process for the preparation of polyester/polycarbonate copolymers | GENERAL ELECTRIC COMPANY (US) | 1988-07-06 | — | — | EP | claimed |
| US-4278576-A | STEARATE COATED CALCIUM CARBONATE | ROHM AND HAAS COMPANY (US) | 1981-07-14 | — | — | US | claimed |