Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL539238 | 0.96 | TSHR (0.48) | TSHRTP53SRD5A2KMT2ACA1 | |
| Terephthalic Acid SCHEMBL28693414 | 0.96 | TSHR (0.48) | TSHRTP53SRD5A2KMT2ACA1 | |
| Terephthalic Acid SCHEMBL29389282 | 0.96 | TSHR (0.48) | TSHRTP53SRD5A2KMT2ACA1 | |
| Terephthalic Acid SCHEMBL6132118 | 0.93 | TSHR (0.44) | TSHRTP53SRD5A2KMT2ACA1 | |
| Benzoic Acid SCHEMBL25227095 | 0.89 | TSHR (0.52) | TSHRTP53SRD5A2KMT2AALDH1A1 | |
| Benzoic Acid SCHEMBL1713123 | 0.89 | TSHR (0.52) | TSHRTP53SRD5A2KMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL247734 | 0.86 | CYP2C9 (0.44) | TSHRTP53SRD5A2KMT2ACA1 | |
| Ethylene Glycol SCHEMBL2299685 | 0.85 | MAPT (0.39) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL3178452 | 0.84 | TSHR (0.63) | TSHRTP53SRD5A2KMT2ACA1 | |
| Isophthalic Acid SCHEMBL8734977 | 0.82 | CYP2C9 (0.46) | KMT2ACA1CA2CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-210264733-U | Tunnel secondary lining polymer transparent plug plate device | 四川皓德斯新材料科技有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-101327673-B | Metal composite board for injection moulding | BYD CO LTD | 2012-09-05 | — | — | CN | claimed |
| CN-101796096-A | Polyethylene terephthalate graft copolymer resin and method for producing molded article thereof | FTEX INC | 2010-08-04 | — | — | CN | claimed |
| US-7718733-B2 | Optically clear polycarbonate polyester compositions | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-05-18 | — | — | US | claimed |
| CN-101327673-A | Metal composite board for injection moulding | BYD CO LTD (CN) | 2008-12-24 | — | — | CN | claimed |
| EP-1987100-A2 | FLAME RETARDANT RESIN COMPOSITION | Sabic Innovative Plastics IP B.V. (NL) | 2008-11-05 | — | — | EP | claimed |
| WO-2007097866-A2 | FLAME RETARDANT RESIN COMPOSITION | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2007-08-30 | — | — | WO | claimed |
| US-20070197696-A1 | Flame retardant resin composition | GENERAL ELECTRIC COMPANY | 2007-08-23 | — | — | US | claimed |
| EP-1543075-A1 | POLYCARBONATE/POLYESTER COPOLYMER BLENDS AND PROCESS FOR MAKING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-06-22 | — | — | EP | claimed |
| US-20040127653-A1 | Polycarbonate/polyester copolymer blends and process for making thereof | GENERAL ELECTRIC COMPANY | 2004-07-01 | — | — | US | claimed |
| WO-2004020523-A1 | POLYCARBONATE/POLYESTER COPOLYMER BLENDS AND PROCESS FOR MAKING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| US-12036807-B2 | Thermal transfer sheet, intermediate transfer medium, and printed object manufacturing method | DAI NIPPON PRINTING CO., LTD. (JP) | 2024-07-16 | — | — | US | disclosed |
| CN-110080804-B | Transparent end cap device of tunnel second lining polymer | 四川皓德斯新材料科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-4172268-B1 | CHEMICALLY-RESISTANT FLAME RETARDANT COMPOSITIONS | SHPP GLOBAL TECH BV (NL) | 2024-07-03 | — | — | EP | disclosed |
| US-11912053-B2 | Thermal transfer sheet, coating liquid for release layer, and method for producing thermal transfer sheet | DAI NIPPON PRINTING CO., LTD. (JP) | 2024-02-27 | — | — | US | disclosed |
| EP-0803537-A2 | Impact modified polyester-polycarbonate molding compositions | GENERAL ELECTRIC COMPANY (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0787769-A2 | Impact modified polycarbonate and/or polyester compositions with high weather resistance | GENERAL ELECTRIC COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0705875-A1 | Universal masterbatch | CABOT CORPORATION (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5500261-A | MULTILAYER POLYESTER CONTAINER | KAO CORPORATION (JP) | 1996-03-19 | — | — | US | disclosed |
| WO-1996006882-A1 | UNIVERSAL MASTERBATCH | CABOT CORPORATION (US) | 1996-03-07 | — | — | WO | disclosed |