SCHEMBL539286

SCHEMBL539286

CC(Cl)(Cl)SSC(C)(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246317 0.70
Trichloroethane SCHEMBL10482068 0.65 TSHR (1.00) TSHRTHRB
SCHEMBL7490 0.65
Trichloroethane SCHEMBL64609 0.65
Trichloroethane SCHEMBL16434 0.65
SCHEMBL90709 0.65
Trichloroethane SCHEMBL3833855 0.65 TSHR (1.00) TSHRTHRB
SCHEMBL10649555 0.65
Trichloroethane SCHEMBL25372481 0.60
Trichloroethane SCHEMBL8720044 0.60 TSHR (0.86) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778846-B2 Composition, device and associated method GENERAL ELECTRIC COMPANY (US) 2014-07-15 US disclosed
US-8778845-B2 Composition, device and associated method GENRAL ELECTRIC COMPANY (US) 2014-07-15 US disclosed
US-8765643-B2 Composition, device and associated method GENERAL ELECTRIC COMPANY (US) 2014-07-01 US disclosed
US-8741813-B2 Composition, device and associated method GENERAL ELECTRIC COMPANY (US) 2014-06-03 US disclosed
US-20140072956-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2014-03-13 US disclosed
EP-2241440-B1 Article acting as a barrier to noxious agents, laminate and associated production method GEN ELECTRIC (US) 2013-05-29 EP disclosed
US-8425858-B2 Detection apparatus and associated method MORPHO DETECTION, INC. (US) 2013-04-23 US disclosed
US-20120122735-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2012-05-17 US disclosed
US-20120122733-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2012-05-17 US disclosed
US-20120122734-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2012-05-17 US disclosed
US-20090155564-A1 ARTICLE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2009-06-18 US disclosed
US-20090117367-A1 ARTICLE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2009-05-07 US disclosed
WO-2009042264-A1 FILTER AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2009-04-02 WO disclosed
WO-2008127779-A2 COMPOSITION AND METHOD FOR THE DETECTION OF ANALYTES USING POLYMERIZATION BASED SIGNAL AMPLIFICATION GENERAL ELECTRIC COMPANY (US) 2008-10-23 WO disclosed
WO-2008070639-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-06-12 WO disclosed
US-20070207284-A1 Barrier article and method MCCLINTIC SHAWN A 2007-09-06 US disclosed
US-20070086916-A1 Faceted structure, article, sensor device, and method GENERAL ELECTRIC COMPANY (US) 2007-04-19 US disclosed
US-20070086915-A1 Detection apparatus and associated method GENERAL ELECTRIC COMPANY (US) 2007-04-19 US disclosed
US-20060210440-A1 Opto-acoustic sensor system and associated method GENERAL ELECTRIC COMPANY (US) 2006-09-21 US disclosed
US-20060198760-A1 Opto-acoustic sensor device and associated method GENERAL ELECTRIC COMPANY (US) 2006-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122734-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD KIT, S100B, CACYBP TSHR 4831/4885THRB 4057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.