Glutarate

Glutarate

SCHEMBL5393154

O=C(O)CCCC(=O)O.c1cc2ccc1o2

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.55
LMNA P02545 3/20 0.48
HDAC3 O15379 3/20 0.46
HDAC4 P56524 3/20 0.46
HDAC1 Q13547 3/20 0.46
HDAC7 Q8WUI4 3/20 0.46
HDAC2 Q92769 3/20 0.46
HDAC10 Q969S8 3/20 0.46
HDAC11 Q96DB2 3/20 0.46
HDAC8 Q9BY41 3/20 0.46
HDAC6 Q9UBN7 3/20 0.46
HDAC9 Q9UKV0 3/20 0.46
HDAC5 Q9UQL6 3/20 0.46
MAPK1 P28482 2/20 0.46
ADRA1A P35348 1/20 0.46
SLC6A3 Q01959 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 2/20 0.46
NFKB1 P19838 1/20 0.46
PMP22 Q01453 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL5395454 0.95 LMNA (0.55) SLC22A6LMNAHDAC3HDAC4HDAC1
Glutarate SCHEMBL27824860 0.74 SLC22A6 (0.85) SLC22A6LMNAHDAC3HDAC4HDAC1
Glutarate SCHEMBL158774 0.74 SLC22A6 (1.00) SLC22A6LMNAHDAC3HDAC4HDAC1
Glutarate SCHEMBL7414 0.74
Glutarate SCHEMBL6701735 0.74
Glutarate SCHEMBL27601182 0.74 SLC22A6 (1.00) SLC22A6LMNAHDAC3HDAC4HDAC1
Glutarate SCHEMBL250428 0.72 FFAR1 (0.61) SLC22A6LMNAHDAC3HDAC4HDAC1
Terephthalic Acid SCHEMBL8815351 0.72 TSHR (0.63) SLC22A6LMNAHDAC3HDAC4HDAC1
Glutarate SCHEMBL5603986 0.71 SLC22A6 (0.92) SLC22A6LMNAHDAC3HDAC4HDAC1
Glutarate SCHEMBL106538 0.71 SLC22A6 (0.92) SLC22A6LMNAHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312299-B2 Bioabsorbabl, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-12-25 US claimed
US-7301001-B2 Bioabsorbable, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-11-27 US claimed
US-20070123689-A1 Bioabsorbable, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2007-05-31 US claimed
US-20070100123-A1 Bioabsorbable, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2007-05-03 US claimed
US-7186789-B2 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-03-06 US claimed
JP-2007501893-A 2007-02-01 JP claimed
EP-1636290-A1 BIOABSORBABLE, BIOBENEFICIAL POLYESTER POLYMERS FOR USE IN DRUG ELUTING STENT COATINGS ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2006-03-22 EP claimed
WO-2005000939-A1 BIOABSORBABLE, BIOBENEFICIAL POLYESTER POLYMERS FOR USE IN DRUG ELUTING STENT COATINGS ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2005-01-06 WO claimed
US-20040253203-A1 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2004-12-16 US claimed
US-7312299-B2 Bioabsorbabl, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-12-25 US disclosed
US-7301001-B2 Bioabsorbable, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-11-27 US disclosed
US-20070123689-A1 Bioabsorbable, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2007-05-31 US disclosed
US-20070100123-A1 Bioabsorbable, biobeneficial polyester polymers for stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2007-05-03 US disclosed
US-7186789-B2 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-03-06 US disclosed
EP-1636290-A1 BIOABSORBABLE, BIOBENEFICIAL POLYESTER POLYMERS FOR USE IN DRUG ELUTING STENT COATINGS ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2006-03-22 EP disclosed
WO-2005000939-A1 BIOABSORBABLE, BIOBENEFICIAL POLYESTER POLYMERS FOR USE IN DRUG ELUTING STENT COATINGS ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2005-01-06 WO disclosed
US-20040253203-A1 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2004-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040253203-A1 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings CEL, CD44, PBDC1 SLC22A6 1112/4885LMNA 4119/4885HDAC3 3492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.