Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.40 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363020 | 0.87 | KIF11 (0.46) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| SCHEMBL13956817 | 0.78 | KIF11 (0.59) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| SCHEMBL4367300 | 0.74 | KIF11 (0.46) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| SCHEMBL4363019 | 0.73 | KIF11 (0.45) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| SCHEMBL13956818 | 0.71 | KIF11 (0.68) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| Hydrochloric Acid SCHEMBL4371126 | 0.70 | KIF11 (0.68) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| SCHEMBL13971404 | 0.70 | KIF11 (0.57) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| SCHEMBL13956803 | 0.67 | P2RX7 (0.42) | KIF11CYP3A4CTSSPPARASCN9A | |
| SCHEMBL13956801 | 0.67 | KIF11 (0.64) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 | |
| SCHEMBL13956808 | 0.66 | KIF11 (0.61) | KIF11KIF23CYP3A4MAP1LC3BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166595-B2 | Compounds, methods and compositions | CYTOKINETICS, INC. (US) | 2007-01-23 | — | — | US | disclosed |