Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397192 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNAEGFRHTTGAA | |
| SCHEMBL5394948 | 0.93 | TNFSF11 (0.42) | ALDH1A1LMNAEGFRHTTGAA | |
| SCHEMBL5394950 | 0.93 | TNFSF11 (0.42) | ALDH1A1LMNAEGFRHTTGAA | |
| SCHEMBL5403690 | 0.92 | EGFR (0.31) | EGFR | |
| SCHEMBL5403688 | 0.92 | EGFR (0.31) | EGFR | |
| SCHEMBL5412146 | 0.92 | EGFR (0.40) | ALDH1A1LMNAEGFRGAAMAPT | |
| SCHEMBL5412149 | 0.92 | EGFR (0.40) | ALDH1A1LMNAEGFRGAAMAPT | |
| SCHEMBL5400111 | 0.91 | ALDH1A1 (0.31) | ALDH1A1LMNAEGFRMAPTMAPK1 | |
| SCHEMBL5400109 | 0.91 | ALDH1A1 (0.31) | ALDH1A1LMNAEGFRMAPTMAPK1 | |
| SCHEMBL14542890 | 0.89 | PDE4A (0.32) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208142-B2 | Indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2007-04-24 | — | — | US | claimed |
| CN-1246303-C | Indanylidene compounds | THIMRASS KG (DE) | 2006-03-22 | — | — | CN | claimed |
| EP-1466892-A1 | Novel indanylidene compounds | Symrise GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | claimed |
| EP-1341752-B1 | NOVEL INDANYLIDENE COMPOUNDS | SYMRISE GMBH & CO KG (DE) | 2004-08-04 | — | — | EP | claimed |
| CN-1473146-A | Novel indanylidene compounds | ��������ķ������ | 2004-02-04 | — | — | CN | claimed |
| EP-1341752-A1 | NOVEL INDANYLIDENE COMPOUNDS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | claimed |
| US-20020143203-A1 | Novel indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2002-10-03 | — | — | US | claimed |
| WO-2002038537-A1 | NOVEL INDANYLIDENE COMPOUNDS | HAARMANN & REIMER GMBH (DE) | 2002-05-16 | — | — | WO | claimed |
| US-20070185057-A1 | Novel Indanone Compounds | SYMRISE GMBH & CO. KG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-7208142-B2 | Indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2007-04-24 | — | — | US | disclosed |
| CN-1246303-C | Indanylidene compounds | THIMRASS KG (DE) | 2006-03-22 | — | — | CN | disclosed |
| EP-1466892-A1 | Novel indanylidene compounds | Symrise GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | disclosed |
| EP-1341752-B1 | NOVEL INDANYLIDENE COMPOUNDS | SYMRISE GMBH & CO KG (DE) | 2004-08-04 | — | — | EP | disclosed |
| CN-1473146-A | Novel indanylidene compounds | ��������ķ������ | 2004-02-04 | — | — | CN | disclosed |
| US-20020143203-A1 | Novel indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185057-A1 | Novel Indanone Compounds | CUTA, NISCH, TYR | ALDH1A1 434/4885LMNA 713/4885EGFR 1186/4885 |
| US-20020143203-A1 | Novel indanylidene compounds | CUTA, NISCH, ERCC4 | ALDH1A1 373/4885LMNA 518/4885EGFR 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.