Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 17/20 | 0.57 |
| ▸ | CTSS | P25774 | 16/20 | 0.57 |
| ▸ | CTSB | P07858 | 13/20 | 0.57 |
| ▸ | CTSK | P43235 | 11/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5392764 | 0.83 | CTSL (0.48) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2820824 | 0.81 | CTSL (0.71) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2820825 | 0.81 | CTSL (0.71) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2820828 | 0.81 | CTSL (0.71) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2820741 | 0.80 | CTSS (0.59) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2820743 | 0.80 | CTSS (0.59) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2821047 | 0.77 | CTSL (0.89) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2822122 | 0.77 | CTSL (0.71) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2822120 | 0.77 | CTSL (0.71) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2821048 | 0.77 | CTSL (0.89) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007505920-A | — | — | 2007-03-15 | — | — | JP | claimed |
| EP-1663958-A2 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005028429-A2 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | claimed |
| EP-1663958-A2 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005028429-A2 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | disclosed |