Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MASP2 | O00187 | 1/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528714 | 0.92 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL4388269 | 0.76 | KDM4E (0.55) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL172216 | 0.75 | NPC1 (1.00) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL30561047 | 0.75 | NPC1 (1.00) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL30634854 | 0.75 | NPC1 (1.00) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL16403339 | 0.74 | PLAUR (0.61) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| Water SCHEMBL9817804 | 0.73 | NPC1 (0.95) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL29034384 | 0.73 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL9214713 | 0.73 | ALDH1A1 (0.68) | ALDH1A1NPC1RAB9ANPSR1KDM4E | |
| SCHEMBL1705977 | 0.71 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9ANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2665 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | claimed |
| US-20240189306-A1 | SHP2 INHIBITOR AND USE THEREOF | KANAPH THERAPEUTICS INC. (KR) | 2024-06-13 | — | — | US | claimed |
| WO-2024104425-A1 | KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| EP-4368625-A1 | SHP2 INHIBITOR AND USE THEREOF | Kanaph Therapeutics Inc. (KR) | 2024-05-15 | — | — | EP | claimed |
| CN-117916242-A | SHP2 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117551221-A | Benzimidazolyl chitosan quaternary ammonium salt derivative and preparation and application thereof | 中国科学院烟台海岸带研究所 | 2024-02-13 | — | — | CN | claimed |
| US-20240025892-A1 | SALT INDUCIBLE KINASE INHIBITORS | THE GENERAL HOSPITAL CORPORATION | 2024-01-25 | — | — | US | claimed |
| CN-115043829-B | Indole compound and preparation method and application thereof | 河南农业大学 | 2023-07-25 | — | — | CN | claimed |
| EP-4192459-A1 | SALT INDUCIBLE KINASE INHIBITORS | The General Hospital Corporation (US) | 2023-06-14 | — | — | EP | claimed |
| EP-0611375-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1994-08-24 | — | — | EP | claimed |
| EP-0417555-B1 | Pentamethine dyes and derivatives | BAYER AG (DE) | 1993-11-03 | — | — | EP | claimed |
| WO-1993009135-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1993-05-13 | — | — | WO | claimed |
| US-5118814-A | Pressure sensitive and heat sensitive recording media | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| EP-0217256-B1 | METHOD FOR QUENCHING FLUORESCENCE, AND CATIONIC DERIVATIVES OF NAPHTHALENE-PERI-DICARBOXAMIDE | BAYER AG (DE) | 1991-03-06 | — | — | EP | claimed |
| EP-0201221-B1 | 6-(1-ACYL-1-HYDROXY METHYL) PENICILLANIC ACID DERIVATIVES | PFIZER INC. (US) | 1990-08-01 | — | — | EP | claimed |
| EP-0370198-A1 | Tetraindolyl heptamethine derivatives | BAYER AG (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0217256-A2 | Method for quenching fluorescence, and cationic derivatives of naphthalene-peri-dicarboxamide | BAYER AG (DE) | 1987-04-08 | — | — | EP | claimed |
| EP-0173377-A2 | Pyrimidone compounds, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-03-05 | — | — | EP | claimed |
| EP-0086647-A2 | Pyrimidone compounds, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-08-24 | — | — | EP | claimed |