Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289504 | 0.90 | CHRM3 (0.46) | CHRM3CHRM2CHRM1POLBCHRM4 | |
| SCHEMBL28905886 | 0.84 | CHRM3 (0.54) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL2763579 | 0.83 | POLB (0.62) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL25908477 | 0.83 | CHRM3 (0.42) | CHRM3CHRM2CHRM1MEN1KMT2A | |
| Oxitefonium SCHEMBL29388802 | 0.82 | CHRM1 (0.73) | CHRM3CHRM2CHRM1POLBMEN1 | |
| Oxitefonium SCHEMBL2733669 | 0.81 | CHRM1 (0.76) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL26529315 | 0.81 | CHRM3 (0.42) | CHRM3CHRM2CHRM1POLBCHRM4 | |
| SCHEMBL14166200 | 0.80 | CHRM2 (0.50) | CHRM3CHRM2CHRM1POLBMEN1 | |
| SCHEMBL2130216 | 0.79 | PIN1 (0.44) | CHRM3CHRM2CHRM1POLBKMT2A | |
| SCHEMBL14408517 | 0.79 | CHRM3 (0.48) | CHRM3CHRM2CHRM1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39820-E1 | As anticholinergics, administered by inhalation, they are useful for the treatment of chronic obstructive bronchitis or slight to moderately severe asthma; administered by the intravenous or oral routes, they are useful for the treatment of vagally induced sinus bradycardia | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-09-04 | — | — | US | disclosed |
| US-5770738-A | ANTICHOLINERGIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-06-23 | — | — | US | disclosed |
| US-5654314-A | RESPIRATORY SYSTEM DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 1997-08-05 | — | — | US | disclosed |
| US-5610163-A | ANTICHOLINERGIC AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1997-03-11 | — | — | US | disclosed |