Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289504 | 0.87 | CHRM3 (0.46) | CHRM3CHRM2CHRM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL26529315 | 0.83 | CHRM3 (0.42) | CHRM3CHRM2CHRM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5399482 | 0.83 | CHRM3 (0.51) | CHRM3CHRM2CHRM1ALDH1A1MAPT | |
| SCHEMBL25908533 | 0.78 | CHRM3 (0.49) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL25908478 | 0.78 | CHRM3 (0.49) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL16053656 | 0.76 | CHRM3 (0.47) | CHRM3CHRM2CHRM1ALDH1A1HPGD | |
| SCHEMBL25908761 | 0.75 | CHRM3 (0.47) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL25908710 | 0.75 | CHRM3 (0.47) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2130216 | 0.74 | PIN1 (0.44) | CHRM3CHRM2CHRM1ALDH1A1HPGD | |
| SCHEMBL11430256 | 0.73 | ALDH1A1 (0.49) | CHRM3CHRM2CHRM1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219485-A1 | FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-08-02 | — | — | EP | disclosed |