Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357564 | 0.92 | CDK1 (0.36) | LMNACDK1 | |
| SCHEMBL5432674 | 0.85 | MAP2K1 (0.32) | — | |
| SCHEMBL5408720 | 0.85 | MAPT (0.38) | LMNAALDH1A1KDM4E | |
| SCHEMBL5396481 | 0.85 | LMNA (0.33) | LMNA | |
| SCHEMBL5405380 | 0.81 | HRH4 (0.34) | ALDH1A1CDK1 | |
| SCHEMBL5441226 | 0.80 | LMNA (0.34) | LMNA | |
| SCHEMBL14357594 | 0.80 | TLR7 (0.31) | LMNA | |
| SCHEMBL5707080 | 0.80 | CYP1A2 (0.35) | KDM4ECDK1 | |
| SCHEMBL5406499 | 0.78 | MAPT (0.38) | ALDH1A1KDM4E | |
| SCHEMBL5401517 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300469-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-11-27 | — | — | US | disclosed |
| US-7300469-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-11-27 | — | — | US | disclosed |
| US-7300469-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-11-27 | — | — | US | disclosed |