Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390685 | 0.83 | GSK3B (1.00) | GSK3BSMN1; SMN2MEN1KMT2ACDC7 | |
| SCHEMBL5387930 | 0.81 | GSK3B (1.00) | GSK3BSMN1; SMN2MEN1KMT2ACDC7 | |
| SCHEMBL5400563 | 0.80 | PDE10A (0.48) | GSK3BCDC7HTR1BHRH1 | |
| SCHEMBL5375274 | 0.79 | XDH (0.55) | GSK3BMEN1KMT2ACDC7ALDH1A1 | |
| SCHEMBL5376095 | 0.79 | GSK3B (1.00) | GSK3BSMN1; SMN2MEN1KMT2ACDC7 | |
| SCHEMBL5380514 | 0.78 | GSK3B (0.84) | GSK3BSMN1; SMN2CDC7XDHDYRK3 | |
| SCHEMBL5386254 | 0.76 | GSK3B (1.00) | GSK3BSMN1; SMN2CDC7XDHDYRK3 | |
| SCHEMBL3854866 | 0.75 | SMN1; SMN2 (0.74) | GSK3BSMN1; SMN2MEN1KMT2ACDC7 | |
| SCHEMBL5381263 | 0.75 | GSK3B (0.92) | GSK3BSMN1; SMN2CDC7XDHDYRK3 | |
| SCHEMBL5386572 | 0.74 | GSK3B (1.00) | GSK3BSMN1; SMN2MEN1KMT2ACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |