Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.57 |
| ▸ | GCGR | P47871 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382895 | 0.92 | GSK3B (0.56) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5380586 | 0.91 | GSK3B (0.55) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5392064 | 0.85 | GSK3B (0.59) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5400586 | 0.82 | GSK3B (0.58) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5382372 | 0.77 | MAPK13 (0.56) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5382897 | 0.76 | GSK3B (0.57) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5380589 | 0.75 | GSK3B (0.56) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5392069 | 0.73 | GSK3B (0.59) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5387928 | 0.73 | GSK3B (0.65) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5387930 | 0.73 | GSK3B (1.00) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |