Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.55 |
| ▸ | GCGR | P47871 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382895 | 0.94 | GSK3B (0.56) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5400580 | 0.91 | GSK3B (0.57) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5392064 | 0.86 | GSK3B (0.59) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5380589 | 0.83 | GSK3B (0.56) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5380270 | 0.81 | MAPK13 (0.51) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5382897 | 0.77 | GSK3B (0.57) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5400586 | 0.75 | GSK3B (0.58) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5392069 | 0.74 | GSK3B (0.59) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5390448 | 0.73 | MAPK13 (0.54) | GSK3BGCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5388030 | 0.72 | GSK3B (0.50) | GSK3BMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |