Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386893 | 0.81 | ALOX15 (0.44) | CDC7GCGRMAPK14CDK2GSK3B | |
| SCHEMBL5391770 | 0.81 | CDC7 (0.48) | CDC7GCGRMAPK14CCNA2CDK2 | |
| SCHEMBL5400621 | 0.80 | GSK3B (0.54) | CDC7APAF1CASP3CASP6SENP8 | |
| SCHEMBL5400026 | 0.78 | GCGR (0.42) | CDC7GCGRMAPK14CDK2PIM1 | |
| SCHEMBL5391510 | 0.78 | FABP4 (0.53) | CDC7KDM4CPIM1GSK3B | |
| SCHEMBL5384156 | 0.77 | CDC7 (0.44) | CDC7GCGRMAPK14CDK2GSK3B | |
| SCHEMBL5379882 | 0.76 | MAPT (0.47) | CDC7GCGRMAPK14GSK3B | |
| SCHEMBL5387918 | 0.72 | GSK3B (0.41) | CDC7GCGRGSK3B | |
| SCHEMBL5399975 | 0.71 | CDC7 (0.48) | CDC7GCGRMAPK14CDK2GSK3B | |
| SCHEMBL5381545 | 0.71 | CDC7 (0.59) | CDC7KDM4CMAPK14CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |