O-Tolylamine

O-Tolylamine

SCHEMBL7799079

Cc1ccccc1N.O=P(O)(O)Oc1c[nH]c2ccccc12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.47
CFTR P13569 1/20 0.42
ATM Q13315 2/20 0.41
NPC1 O15118 1/20 0.41
PBRM1 Q86U86 1/20 0.40
HTR2A P28223 2/20 0.39
HTR1A P08908 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
CTNNB1 P35222 1/20 0.39
WNT3A P56704 1/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NR4A2 P43354 1/20 0.38
CREBBP Q92793 1/20 0.38
GFER P55789 1/20 0.38
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Tolylamine SCHEMBL6636539 1.00 SLC22A6 (0.47) SLC22A6CFTRATMNPC1PBRM1
SCHEMBL31034497 0.86 SLC22A6 (0.56) SLC22A6ATMPBRM1HTR2AHTR1A
SCHEMBL540158 0.86 SLC22A6 (0.56) SLC22A6ATMPBRM1HTR2AHTR1A
O-Tolylamine SCHEMBL30712038 0.86 NR4A2 (0.41) SLC22A6CFTRHTR2AHTR1AHTR2C
SCHEMBL458847 0.84 SLC22A6 (0.47) SLC22A6NPC1PBRM1HTR2AHTR1A
SCHEMBL7800278 0.84 SLC22A6 (0.47) SLC22A6NPC1PBRM1HTR2AHTR1A
SCHEMBL30903953 0.84 SLC22A6 (0.47) SLC22A6NPC1PBRM1HTR2AHTR1A
SCHEMBL463226 0.78 SLC22A6 (0.46) SLC22A6ATMPBRM1HTR2AHTR1A
O-Tolylamine SCHEMBL1655431 0.77 HTR2A (0.37) HTR2AHTR1AHTR2CHTR2BCYP3A4
O-Tolylamine SCHEMBL4096509 0.77 HTR2A (0.37) HTR2AHTR1AHTR2CHTR2BCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109600991-A Immunogenic composition comprising survivin peptide 万可思乐研究股份有限公司 2019-04-09 CN disclosed
EP-0775215-B1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES OR THIOINDOXYL SUBSTRATES MEDILITE DIAGNOSTIKA (US) 2001-12-19 EP disclosed
EP-0775215-A1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES MEDILITE DIAGNOSTIKA (US) 1997-05-28 EP disclosed
US-5589328-A CHEMICAL INTERMEDIATES OR METABOLITES FOR IMMUNOASSAY MEDILITE DIAGNOSTIKA 1996-12-31 US disclosed
WO-1996004400-A1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES MEDILITE DIAGNOSTIKA (US) 1996-02-15 WO disclosed