Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983429 | 0.97 | HTR7 (0.72) | HTR7ABCB1TMEM97SIGMAR1GRIN1 | |
| Hydrochloric Acid SCHEMBL4218491 | 0.96 | HTR7 (0.71) | HTR7ABCB1TMEM97SIGMAR1GRIN1 | |
| SCHEMBL10035562 | 0.94 | HTR7 (0.63) | HTR7ABCB1GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL2141212 | 0.93 | HTR7 (0.62) | HTR7ABCB1GRIN1GRIN2B | |
| SCHEMBL10035620 | 0.92 | HTR7 (0.61) | HTR7ABCB1 | |
| Hydrochloric Acid SCHEMBL2137773 | 0.91 | HTR7 (0.60) | HTR7ABCB1 | |
| SCHEMBL8981592 | 0.91 | HTR7 (0.64) | HTR7ABCB1TMEM97SIGMAR1GRIN1 | |
| SCHEMBL10035595 | 0.90 | ABCB1 (0.64) | HTR7ABCB1 | |
| SCHEMBL10035624 | 0.90 | MBTD1 (0.59) | HTR7ABCB1TMEM97SIGMAR1 | |
| SCHEMBL2138032 | 0.90 | HTR7 (0.57) | HTR7ABCB1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211584-B2 | 5-HT7 receptor ligands | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | claimed |
| US-7211584-B2 | 5-HT7 receptor ligands | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | disclosed |
| US-7211584-B2 | 5-HT7 receptor ligands | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | disclosed |