Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036126 | 0.92 | ALDH1A1 (0.66) | ALDH1A1RECQLATMPOLBNPSR1 | |
| SCHEMBL16143340 | 0.88 | ALDH1A1 (0.57) | ALDH1A1RECQLATMPOLBNPSR1 | |
| SCHEMBL16143372 | 0.86 | ALDH1A1 (0.56) | ALDH1A1RECQLATMPOLBNPSR1 | |
| SCHEMBL12912525 | 0.84 | ALDH1A1 (0.52) | ALDH1A1RECQLATMPOLBNPSR1 | |
| SCHEMBL7800751 | 0.83 | ALDH1A1 (0.60) | ALDH1A1RECQLATMKDM4EPKM | |
| SCHEMBL13691613 | 0.82 | ALDH1A1 (0.57) | ALDH1A1RECQLATMPOLBNPSR1 | |
| SCHEMBL7797578 | 0.82 | ALDH1A1 (0.50) | ALDH1A1RECQLATMPOLBNPSR1 | |
| SCHEMBL16143378 | 0.82 | ALDH1A1 (0.46) | ALDH1A1RECQLATMPOLBNPSR1 | |
| SCHEMBL1925793 | 0.80 | POLB (0.58) | ALDH1A1POLBNPSR1KDM4EMAPT | |
| SCHEMBL6506349 | 0.80 | ALDH1A1 (0.64) | ALDH1A1RECQLATMKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511473-B1 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| US-7169817-B2 | Bis-aromatic alkanols | IRM LLC (BM) | 2007-01-30 | — | — | US | disclosed |
| EP-1511473-A2 | BIS-AROMATIC ALKANOLS | Novartis AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| US-20040048857-A1 | Treatment and/or prevention of diseases or disorders mediated by lymphocyte interactions. | IRM LLC (BM) | 2004-03-11 | — | — | US | disclosed |
| WO-2003099192-A2 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048857-A1 | Treatment and/or prevention of diseases or disorders mediated by lymphocyte interactions. | CD4, HLA-DRB1, MALT1 | ALDH1A1 1177/4885RECQL 1702/4885ATM 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.