Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL540419 | 0.83 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL12541175 | 0.82 | ALDH1A1 (0.36) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL4833319 | 0.80 | ESR1 (0.46) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL540935 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL945915 | 0.78 | ALDH1A1 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL18261205 | 0.78 | ALDH1A1 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL540391 | 0.77 | ALDH1A1 (0.47) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6471561 | 0.77 | ALDH1A1 (0.42) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL28502709 | 0.77 | ALDH1A1 (0.42) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL6757539 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656198-B | Process for the preparation of a particulate bimodal polyethylene product | TOTAL PETROCHEMICALS RES FELUY | 2014-05-28 | — | — | CN | claimed |
| CN-102656198-A | Process for the preparation of a particulate bimodal polyethylene product | TOTAL PETROCHEMICALS RES FELUY | 2012-09-05 | — | — | CN | claimed |
| EP-1613665-A1 | SUPPORTED METALLOCENE CATALYSTS | FINA TECHNOLOGY, INC. (US) | 2006-01-11 | — | — | EP | claimed |
| US-6855783-B2 | Supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2005-02-15 | — | — | US | claimed |
| WO-2004092225-A1 | SUPPORTED METALLOCENE CATALYSTS | FINA TECHNOLOGY, INC. (US) | 2004-10-28 | — | — | WO | claimed |
| US-20040204310-A1 | Supported metallocene catalysts | FINA TECHNOLOGY, INC. | 2004-10-14 | — | — | US | claimed |
| CN-116199813-A | Long chain branched polypropylene and preparation method thereof | 中国科学院化学研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-111868116-B | Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof | 三井化学株式会社 | 2022-12-09 | — | — | CN | disclosed |
| CN-111217950-B | Poly-alpha-olefin having uniform structure and method for preparing same | DL化学株式会社 | 2022-09-20 | — | — | CN | disclosed |
| CN-111249059-B | Tooth socket | 三井化学株式会社 | 2022-05-17 | — | — | CN | disclosed |
| CN-111265357-B | Tooth socket | 三井化学株式会社 | 2022-04-19 | — | — | CN | disclosed |
| CN-110312618-B | Laminated body | 三井化学株式会社 | 2021-09-07 | — | — | CN | disclosed |
| CN-110325360-B | Laminated body | 三井化学株式会社 | 2021-07-20 | — | — | CN | disclosed |
| EP-1614699-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | Mitsui Chemicals, Inc. (JP) | 2006-01-11 | — | — | EP | disclosed |
| EP-1613665-A1 | SUPPORTED METALLOCENE CATALYSTS | FINA TECHNOLOGY, INC. (US) | 2006-01-11 | — | — | EP | disclosed |
| US-20050228155-A1 | Metallocene compound, process for preparing metallocene compund, olefin polymerization catalyst, process for preparing polyolefin, and polyolefin | MITSUI CHEMICALS, INC. (JP) | 2005-10-13 | — | — | US | disclosed |
| US-6855783-B2 | Supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2004092225-A1 | SUPPORTED METALLOCENE CATALYSTS | FINA TECHNOLOGY, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| US-20040204310-A1 | Supported metallocene catalysts | FINA TECHNOLOGY, INC. | 2004-10-14 | — | — | US | disclosed |
| EP-1138687-A1 | METALLOCENE COMPOUND, PROCESS FOR PRODUCING METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |