Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.38 |
| ▸ | HTR6 | P50406 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.34 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334906 | 0.94 | HTR6 (0.40) | PTGDR2PTGDRHTR6ALDH1A1MAPT | |
| SCHEMBL5424101 | 0.91 | PKM (0.35) | PTGDR2PTGDRHTR6 | |
| SCHEMBL5407866 | 0.87 | PTGDR2 (0.52) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5328962 | 0.85 | PTGDR2 (0.53) | PTGDR2PTGDRHTR6LMNAMAPT | |
| SCHEMBL5329965 | 0.85 | PTGDR2 (0.54) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5328556 | 0.84 | HTR6 (0.50) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5331491 | 0.83 | HTR6 (0.52) | PTGDR2PTGDRHTR6LMNAPER2 | |
| SCHEMBL5425727 | 0.81 | PTGDR2 (0.56) | PTGDR2PTGDRHTR6LMNA | |
| SCHEMBL5402340 | 0.80 | PTGDR2 (0.40) | PTGDR2PTGDRHTR6ALDH1A1MAPT | |
| SCHEMBL5420513 | 0.80 | PTGDR2 (0.44) | PTGDR2PTGDRHTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |