Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5402176 | 0.92 | KDM4E (0.38) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL5366743 | 0.87 | KDM4E (0.42) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL5413352 | 0.85 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Iodide SCHEMBL5406302 | 0.85 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL5398797 | 0.76 | MEN1 (0.44) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL25231228 | 0.75 | MLNR (0.41) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL2958162 | 0.74 | CNR1 (0.44) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Water SCHEMBL10433024 | 0.72 | HTR7 (0.34) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Bromide SCHEMBL14958477 | 0.71 | CYP1A2 (0.43) | KDM4EMAPTMEN1KMT2APOLB | |
| Bromide SCHEMBL14958485 | 0.71 | HRH3 (0.42) | MAPTPOLBHPGDTDP1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | claimed |
| EP-1054657-B1 | AGENT FOR COLORING FIBERS | WELLA AG (DE) | 2004-01-07 | — | — | EP | claimed |
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | disclosed |
| EP-1054657-B1 | AGENT FOR COLORING FIBERS | WELLA AG (DE) | 2004-01-07 | — | — | EP | disclosed |