Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5413352 | 0.98 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Bromide SCHEMBL5410080 | 0.98 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Iodide SCHEMBL5406302 | 0.98 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL5402971 | 0.87 | KDM4E (0.35) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL28685784 | 0.80 | ELANE (0.37) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL15007793 | 0.79 | KDM4E (0.37) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Iodide SCHEMBL29594037 | 0.78 | ELANE (0.36) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Iodide SCHEMBL28522713 | 0.78 | ELANE (0.36) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Bromide SCHEMBL29109663 | 0.78 | KDM4E (0.36) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| Bromide SCHEMBL14958504 | 0.76 | TLR8 (0.39) | KDM4EMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054657-B1 | AGENT FOR COLORING FIBERS | WELLA AG (DE) | 2004-01-07 | — | — | EP | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | KDM4E 1510/4885MAPT 1792/4885MEN1 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.