Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209901 | 0.84 | GPR119 (0.53) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL25221384 | 0.84 | GPR119 (0.53) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL9933572 | 0.84 | GPR119 (0.53) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL13044640 | 0.82 | GPR119 (0.51) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL5409331 | 0.82 | GPR119 (0.48) | GPR119POLBCKS1BSKP1SKP2 | |
| SCHEMBL38663417 | 0.81 | GPR119 (0.50) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL1514908 | 0.81 | GPR119 (0.50) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL9934875 | 0.81 | GPR119 (0.50) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL3638210 | 0.79 | GPR119 (0.47) | GPR119POLBGRM5CKS1BSKP1 | |
| SCHEMBL2083282 | 0.78 | GPR119 (0.57) | GPR119ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |