Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 2/20 | 0.47 |
| ▸ | SKP1 | P63208 | 2/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3638210 | 0.86 | GPR119 (0.47) | GPR119POLBGLSCKS1BSKP1 | |
| SCHEMBL25221384 | 0.85 | GPR119 (0.53) | GPR119POLBCKS1BSKP1SKP2 | |
| SCHEMBL9933572 | 0.85 | GPR119 (0.53) | GPR119POLBCKS1BSKP1SKP2 | |
| SCHEMBL209901 | 0.85 | GPR119 (0.53) | GPR119POLBCKS1BSKP1SKP2 | |
| SCHEMBL9934875 | 0.82 | GPR119 (0.50) | GPR119POLBGLSCKS1BSKP1 | |
| SCHEMBL1514908 | 0.82 | GPR119 (0.50) | GPR119POLBGLSCKS1BSKP1 | |
| SCHEMBL38663417 | 0.82 | GPR119 (0.50) | GPR119POLBGLSCKS1BSKP1 | |
| SCHEMBL5403141 | 0.82 | GPR119 (0.53) | GPR119POLBCKS1BSKP1SKP2 | |
| SCHEMBL1852622 | 0.82 | GLS (0.57) | GPR119GLSCKS1BSKP1SKP2 | |
| SCHEMBL3637549 | 0.79 | IDH1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | GPR119 6/4885POLB 4753/4885GLS 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.