Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15825699 | 0.87 | HCAR2 (0.58) | HCAR2 | |
| SCHEMBL31162505 | 0.74 | HCAR2 (0.50) | HCAR2KDM4EPDE4D | |
| SCHEMBL9956866 | 0.71 | HCAR2 (0.47) | HCAR2P2RX7PDE4D | |
| SCHEMBL6257457 | 0.70 | KDM4E (0.44) | HCAR2CHUKKDM4EPOLBMAPT | |
| SCHEMBL21711399 | 0.69 | DYRK1A (0.46) | HCAR2KDM4EP2RX7PDE4D | |
| SCHEMBL4185273 | 0.67 | ALOX15 (0.44) | HCAR2ALOX15KMT2A | |
| SCHEMBL16586297 | 0.67 | HCAR2 (0.42) | HCAR2ALOX15 | |
| SCHEMBL10864602 | 0.64 | HCAR2 (0.44) | HCAR2ALOX15 | |
| SCHEMBL15592682 | 0.64 | HCAR2 (0.40) | HCAR2KDM4EPDE4D | |
| SCHEMBL8507200 | 0.63 | KDM4E (0.38) | HCAR2KDM4EPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084868-A2 | TREATMENT OF DISORDERS BY ACTIVATION OF THE UNFOLDED PROTEIN RESPONSE | KALYPSYS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |