Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.37 |
| ▸ | CA2 | P00918 | 9/20 | 0.37 |
| ▸ | CA9 | Q16790 | 8/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587280 | 0.93 | SMPD1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL10620537 | 0.93 | SMPD1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2577447 | 0.93 | SMPD1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2583075 | 0.93 | SMPD1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2574889 | 0.93 | SMPD1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2587271 | 0.93 | SMPD1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6610038 | 0.83 | CA1 (0.38) | CA1CA2CA9CA12CA7 | |
| Acetic Acid SCHEMBL9751129 | 0.82 | CES2 (0.43) | FDPSSMPD1 | |
| SCHEMBL11784627 | 0.77 | MEN1 (0.43) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5586422 | 0.76 | FDPS (0.39) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099423-A1 | 1-PYRROLIDINE INDANE DERIVATIVES AS HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-0675915-B1 | PHOTODEFINABLE OPTICAL WAVEGUIDES | AMOCO CORP (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0675915-A1 | PHOTODEFINABLE OPTICAL WAVEGUIDES | AMOCO CORPORATION (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5449742-A | Optical waveguides with cores | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| WO-1994014874-A1 | PHOTODEFINABLE OPTICAL WAVEGUIDES | AMOCO CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |
| US-5317082-A | Polyimides | AMOCO CORPORATION (US) | 1994-05-31 | — | — | US | disclosed |