Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PAM | P19021 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664857 | 0.81 | ALDH1A1 (0.65) | MAPK1L3MBTL1ALDH1A1PAMTSHR | |
| Benzene SCHEMBL9407299 | 0.81 | ALDH1A1 (0.65) | MAPK1L3MBTL1ALDH1A1PAMTSHR | |
| SCHEMBL248113 | 0.81 | ALDH1A1 (0.65) | MAPK1L3MBTL1ALDH1A1PAMTSHR | |
| SCHEMBL11689128 | 0.80 | ALDH1A1 (0.70) | MAPK1L3MBTL1ALDH1A1PAMTSHR | |
| SCHEMBL2877979 | 0.79 | ALDH1A1 (0.63) | MAPK1L3MBTL1ALDH1A1PAMTSHR | |
| SCHEMBL247574 | 0.79 | MAPK1 (0.63) | MAPK1L3MBTL1ALDH1A1PAMTSHR | |
| SCHEMBL155716 | 0.78 | TDP1 (0.68) | MAPK1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27660727 | 0.78 | POLB (0.53) | L3MBTL1ALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL11044523 | 0.78 | CES1 (0.64) | MAPK1L3MBTL1ALDH1A1PAMTSHR | |
| SCHEMBL28232439 | 0.78 | EGFR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107082830-B | Using thioxanthone copper carboxylate as opening \" click-free radical \" one kettle way of photochemical catalyst and oxygen scavenger | 苏州大学 | 2019-03-19 | — | — | CN | claimed |
| CN-108586466-A | A kind of benzene phenodiazine * class HDM2 inhibitor and its preparation method and application | 中国药科大学 | 2018-09-28 | — | — | CN | claimed |
| CN-107082830-A | Utilize opening \" click free radical \" one kettle way of thioxanthone copper carboxylate as photochemical catalyst and oxygen scavenger | 苏州大学 | 2017-08-22 | — | — | CN | claimed |
| CN-107019807-A | The polypeptide radiodiagnosis or medicine of a kind of GPC3 receptor targets | 南方医科大学南方医院 | 2017-08-08 | — | — | CN | claimed |
| WO-2014198241-A1 | THIO-1,2,4-TRIAZOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-12-18 | — | — | WO | claimed |
| CN-101440023-B | Preparation of trans-polyhydroxy diphenyl ethylene | GUANGZHOU INST OF CHEMISTRY | 2011-07-20 | — | — | CN | claimed |
| CN-101962368-A | Cyanurate hapten, artificial antigen and antibody, and preparation method and applications thereof | UNIV SOUTH CHINA AGRICULT | 2011-02-02 | — | — | CN | claimed |
| CN-101440023-A | Preparation of trans-polyhydroxy diphenyl ethylene | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-05-27 | — | — | CN | claimed |
| CN-101268037-A | Asymmetric synthesis of - (+) -3- (aminomethyl) -5-methylhexanoic acid | TEVA PHARMA (IL) | 2008-09-17 | — | — | CN | claimed |
| EP-4565570-A1 | HIGH RELAXIVITY CONTRAST AGENTS AND STEREOSELECTIVE PREPARATION | Portland State University (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030772-A1 | HIGH RELAXIVITY CONTRAST AGENTS AND STEREOSELECTIVE PREPARATION | PORTLAND STATE UNIVERSITY (US) | 2024-02-08 | — | — | WO | disclosed |
| CN-116718707-A | Method for detecting genotoxic impurities in pirenzepine bulk drug | 山东达因海洋生物制药股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| US-11708354-B2 | 2-benzopyrazinyl-n-heteroaryl-2-phenyl-acetamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2023-07-25 | — | — | US | disclosed |
| EP-3558967-B1 | 2-BENZOPYRAZINYL-N-HETEROARYL-2-PHENYL-ACETAMIDE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-03-02 | — | — | EP | disclosed |
| CN-101440023-A | Preparation of trans-polyhydroxy diphenyl ethylene | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-05-27 | — | — | CN | disclosed |
| US-20080287441-A1 | ALPHA-(TRIFLUOROMETHYL-SUBSTITUTED ARYLOXY, ARYLAMINO, ARYLTHIO OR ARYLMETHYL)-TRIFLUOROMETHYL-SUBSTITUTED PHENYLACETIC ACIDS AND DERIVATIVES AS ANTIDIABETIC AGENTS | METABOLEX, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| CN-101128461-A | Imidazo (1, 2-a) pyridine compounds as VEGF-R2 inhibitors | LILLY CO ELI (US) | 2008-02-20 | — | — | CN | disclosed |
| CN-1922143-A | Alpha- (trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl) -trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetics | METABOLEX INC (US) | 2007-02-28 | — | — | CN | disclosed |
| EP-0207845-A1 | Bactericides containing 4-oxopyridocarboxylic acid derivatives and process for their preparation | S.A. PANMEDICA Société dite: (FR) | 1987-01-07 | — | — | EP | disclosed |
| US-4496558-A | Pharmaceutical compositions and methods for producing alpha antagonism | SMITHKLINE BECKMAN CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708354-B2 | 2-benzopyrazinyl-n-heteroaryl-2-phenyl-acetamide compounds | EGFR, ERBB2, ERBB3 | MAPK1 1096/4885L3MBTL1 2592/4885ALDH1A1 2578/4885 |
| US-20080287441-A1 | ALPHA-(TRIFLUOROMETHYL-SUBSTITUTED ARYLOXY, ARYLAMINO, ARYLTHIO OR ARYLMETHYL)-TRIFLUOROMETHYL-SUBSTITUTED PHENYLACETIC ACIDS AND DERIVATIVES AS ANTIDIABETIC AGENTS | SLC5A1, GPR119, SLC5A2 | MAPK1 504/4885L3MBTL1 2582/4885ALDH1A1 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.