Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321149 | 0.89 | ALDH1A1 (0.44) | GAATSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5415952 | 0.85 | ALDH1A1 (0.41) | GAATSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3594182 | 0.84 | SMN1; SMN2 (0.61) | GAAALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL5324911 | 0.79 | ICMT (0.45) | GAATSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31158589 | 0.79 | HTR2A (0.69) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL5321455 | 0.77 | ALDH1A1 (0.45) | GAATSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5393266 | 0.77 | MAPT (0.45) | TSHRALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL5324226 | 0.77 | BCHE (0.42) | GAATSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5325721 | 0.77 | ALDH1A1 (0.43) | GAATSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5328217 | 0.77 | MAPT (0.43) | GAATSHRALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |