Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.41 |
| ▸ | CES1 | P23141 | 10/20 | 0.41 |
| ▸ | CES2 | O00748 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929269 | 1.00 | FAAH (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL5846740 | 0.89 | FAAH (0.44) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL455070 | 0.87 | FAAH (0.52) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL457602 | 0.87 | FAAH (0.52) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28532297 | 0.85 | FAAH (0.43) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL313800 | 0.79 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28608284 | 0.79 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7219610 | 0.79 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL29005882 | 0.79 | FAAH (0.38) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28363537 | 0.78 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413879-B1 | CAPILLARY COMPOSITION FOR TREATING HAIR | L'ORÉAL (FR) | 2017-08-16 | — | — | EP | claimed |
| EP-2413879-A1 | CAPILLARY COMPOSITION FOR TREATING HAIR | L'Oréal (FR) | 2012-02-08 | — | — | EP | claimed |
| WO-2010112682-A1 | CAPILLARY COMPOSITION FOR TREATING HAIR | L'OREAL (FR) | 2010-10-07 | — | — | WO | claimed |
| US-20230414482-A1 | COMPOSITIONS FOR KERATIN FIBERS | L'OREAL (FR) | 2023-12-28 | — | — | US | disclosed |
| EP-4255584-A1 | COMPOSITIONS FOR KERATIN FIBERS | L'OREAL (FR) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022118981-A1 | COMPOSITIONS FOR KERATIN FIBERS | L'OREAL (FR) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022118983-A1 | COMPOSITIONS FOR KERATIN FIBERS | L'OREAL (FR) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022118979-A1 | COMPOSITIONS FOR KERATIN FIBERS | L'OREAL (FR) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022118982-A1 | PROCESS FOR TREATING KERATIN FIBERS | L'OREAL (FR) | 2022-06-09 | — | — | WO | disclosed |
| EP-2236053-B2 | Method for the steam treatment of hair | OREAL (FR) | 2021-03-03 | — | — | EP | disclosed |
| US-20210032387-A1 | EMULSION POLYMERS CROSSLINKED WITH COMPOUNDS CONTAINING TWO OR MORE DICARBONYL-SUBSTITUTED 1 ALKENE UNITS | SIRRUS, INC. | 2021-02-04 | — | — | US | disclosed |
| US-8153257-B2 | Capped particles comprising multi-block copolymers for use in lubricants | PRODUCTIVE RESEARCH LLC (US) | 2012-04-10 | — | — | US | disclosed |
| EP-2413879-A1 | CAPILLARY COMPOSITION FOR TREATING HAIR | L'Oréal (FR) | 2012-02-08 | — | — | EP | disclosed |
| EP-2413880-A1 | CAPILLARY COMPOSITION FOR TREATING HAIR | L'Oréal (FR) | 2012-02-08 | — | — | EP | disclosed |
| US-20110166051-A1 | CAPPED PARTICLES FOR USE IN LUBRICANTS | Productive Research LLC. (US) | 2011-07-07 | — | — | US | disclosed |
| WO-2010112683-A1 | CAPILLARY COMPOSITION FOR TREATING HAIR | L'OREAL (FR) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010112682-A1 | CAPILLARY COMPOSITION FOR TREATING HAIR | L'OREAL (FR) | 2010-10-07 | — | — | WO | disclosed |
| EP-2236053-A1 | Method for the steam treatment of hair | L'Oréal (FR) | 2010-10-06 | — | — | EP | disclosed |
| EP-0904052-B1 | CLEANING, CONDITIONING AND STYLING HAIR CARE COMPOSITIONS | STEPAN CO (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-1997038673-A9 | CLEANING, CONDITIONING AND STYLING HAIR CARE COMPOSITIONS | — | 1998-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230414482-A1 | COMPOSITIONS FOR KERATIN FIBERS | KRT18, HACD3, HACD2 | FAAH 829/4885CES1 3841/4885CES2 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.