⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467320 | 0.78 | KDM4E (0.38) | — | |
| SCHEMBL9414036 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL8554707 | 0.76 | — | — | |
| SCHEMBL16324245 | 0.75 | POLB (0.34) | — | |
| SCHEMBL7764668 | 0.75 | TLR8 (0.33) | — | |
| SCHEMBL9414001 | 0.74 | LMNA (0.49) | — | |
| SCHEMBL9413998 | 0.73 | — | — | |
| SCHEMBL8631252 | 0.72 | NOTUM (0.49) | — | |
| SCHEMBL8810931 | 0.72 | TLR8 (0.41) | — | |
| SCHEMBL7735395 | 0.72 | SMN1; SMN2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585970-A2 | Substituted triazolinones | BAYER AG (DE) | 1994-03-09 | — | — | EP | claimed |
| US-12486248-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-02 | — | — | US | disclosed |
| CN-115557907-B | 2,4, 5-Trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| US-20230365524-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-16 | — | — | US | disclosed |
| US-11713304-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-01 | — | — | US | disclosed |
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| US-20220135536-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-05 | — | — | US | disclosed |
| EP-3532468-B1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AG (DE) | 2022-03-23 | — | — | EP | disclosed |
| US-11130745-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | BAYER AKTIENGELLSCHAFT (DE) | 2021-09-28 | — | — | US | disclosed |
| US-5276162-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| US-5262389-A | Substituted triazolinone herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-16 | — | — | US | disclosed |
| EP-0398096-B1 | SUBSTITUTED TRIAZOLONES | BAYER AG (DE) | 1993-10-13 | — | — | EP | disclosed |
| US-5194084-A | Applying herbicides to vegetation | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5166356-A | Substituted triazolinone herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| US-5149356-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |
| US-5085684-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-5061311-A | SUBSTITUTED TRIAZOLINONE HERBICIDES AND PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0431291-A2 | Sulfonylaminocarbony-triazolinones having substituents attached through sulfur | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0283876-A2 | Substituted triazolinones | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |