Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.96 |
| ▸ | CRHBP | P24387 | 1/20 | 0.96 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341306 | 0.81 | KDM4E (0.70) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL29508342 | 0.78 | KDM4E (0.65) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL81185 | 0.78 | KDM4E (0.65) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL30979203 | 0.78 | KDM4E (0.65) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL1339920 | 0.78 | KDM4E (0.66) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL16892543 | 0.77 | KDM4E (0.59) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11737056 | 0.76 | KDM4E (0.62) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL1361220 | 0.76 | KDM4E (0.62) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL6289306 | 0.76 | KDM4E (0.62) | MAPTKDM4ECRHBPCRHR2ALDH1A1 | |
| SCHEMBL6293125 | 0.76 | KDM4E (0.62) | MAPTKDM4ECRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253133-B2 | Catalyst for polymerization or copolymerization of olefins, preparation and use of the same | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2007-08-07 | — | — | US | disclosed |
| US-20050004331-A1 | Catalyst for polymerization or copolymerization of olefins, preparation and use of the same | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2005-01-06 | — | — | US | disclosed |