Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404818 | 1.00 | ALDH1A1 (0.35) | ALDH1A1IRAK4HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL5410016 | 0.93 | USP2 (0.32) | ALDH1A1HPGDAPOBEC3AAPOBEC3GATM | |
| SCHEMBL5332066 | 0.93 | HRH3 (0.33) | ALDH1A1HPGDATML3MBTL1SYK | |
| SCHEMBL5332073 | 0.93 | HRH3 (0.33) | ALDH1A1HPGDATML3MBTL1SYK | |
| SCHEMBL5410022 | 0.93 | USP2 (0.32) | ALDH1A1HPGDAPOBEC3AAPOBEC3GATM | |
| SCHEMBL14542365 | 0.92 | MAPK1 (0.36) | ALDH1A1HPGD | |
| SCHEMBL5428541 | 0.92 | APOBEC3A (0.33) | ALDH1A1IRAK4HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL5428546 | 0.92 | APOBEC3A (0.33) | ALDH1A1IRAK4HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL14542079 | 0.90 | KDM4E (0.34) | ALDH1A1IRAK4HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL14541940 | 0.90 | APOBEC3A (0.34) | ALDH1A1IRAK4HPGDAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | claimed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |