Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5410016 | 1.00 | USP2 (0.32) | USP2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL5404822 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HPGDL3MBTL1APOBEC3AAPOBEC3G | |
| SCHEMBL5404818 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HPGDL3MBTL1APOBEC3AAPOBEC3G | |
| SCHEMBL5428546 | 0.92 | APOBEC3A (0.33) | USP2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL5428541 | 0.92 | APOBEC3A (0.33) | USP2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL5332073 | 0.91 | HRH3 (0.33) | USP2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL5332066 | 0.91 | HRH3 (0.33) | USP2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL14542079 | 0.90 | KDM4E (0.34) | USP2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL14541940 | 0.90 | APOBEC3A (0.34) | USP2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL14542081 | 0.88 | OPRM1 (0.32) | TDP1APOBEC3AAPOBEC3GSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | claimed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |