SCHEMBL5405032

SCHEMBL5405032

CCCNc1c(N)cnn1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 1/20 0.33
MERTK Q12866 1/20 0.33
ALDH1A1 P00352 2/20 0.30
MAPT P10636 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5402356 0.86 FPR1 (0.34) FPR1
SCHEMBL5408910 0.80 CDK1 (0.37) FPR1ALDH1A1MAPTLMNA
SCHEMBL5399080 0.79 FPR1 (0.32) FPR1
SCHEMBL5396441 0.79
SCHEMBL14357567 0.79 SMN1; SMN2 (0.38) FPR1ALDH1A1MAPT
SCHEMBL5403288 0.78
SCHEMBL5399010 0.78
SCHEMBL5406614 0.76 FPR1 (0.31) FPR1
SCHEMBL5406970 0.76 XDH (0.34) ALDH1A1MAPTLMNA
SCHEMBL5406748 0.75 KAT2B (0.31) FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed