SCHEMBL5405055

SCHEMBL5405055

CCn1ncc(N)c1NCC(O)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.32
BCDIN3D Q7Z5W3 1/20 0.30
ALDH1A1 P00352 1/20 0.30
BLM P54132 1/20 0.30
XDH P47989 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5405419 0.91 PDE4B (0.32) PDE4BBCDIN3DALDH1A1BLMXDH
SCHEMBL5447124 0.88
SCHEMBL5410623 0.88 MAPT (0.38) PDE4BBCDIN3DALDH1A1BLMXDH
SCHEMBL5409807 0.87
Bromide SCHEMBL5402709 0.87 MAPT (0.38) PDE4BBCDIN3DALDH1A1BLMXDH
SCHEMBL5405338 0.85 KDM4E (0.33)
SCHEMBL5402369 0.84
SCHEMBL5406437 0.84 TLR7 (0.32) PDE4BXDH
SCHEMBL5406614 0.81 FPR1 (0.31)
SCHEMBL5403260 0.80 POLB (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US claimed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed