Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 5/20 | 0.45 |
| ▸ | PLTP | P55058 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425246 | 0.86 | MAPT (0.47) | MEN1KMT2AALDH1A1NPSR1KDM4E | |
| SCHEMBL5402842 | 0.85 | DHODH (0.62) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4924746 | 0.85 | MAPT (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5364912 | 0.82 | KMT2A (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5397042 | 0.79 | KMT2A (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5409958 | 0.79 | DHODH (0.51) | MEN1KMT2AALDH1A1LMNAALOX12 | |
| SCHEMBL5369173 | 0.78 | KMT2A (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4929895 | 0.76 | SCD (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5366172 | 0.74 | PTGDR2 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27896455 | 0.73 | MEN1 (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |